A common side effects of medications such as Gleevec is swelling (edema). This usually occurs around the eyes or involve the eyelids, which can become puffy; or the legs, which can become swollen or feel heavy.
There are three types of approaches to treating the underlying defect in CML.
The initial problem is too many white blood cells (WBCs) in the blood. A high WBC count on a blood test is often how CML is first detected.
A common problem among people with CML is joint pain – achiness, stiffness, swelling or pain the bones. Sometimes the problem is just aging, but it can be a symptom of CML itself or the medication you’re taking.
A few years ago, CML researchers started asking themselves two intriguing questions: If imatinib and other TKIs can suppress CML to such an extent that leukemia is no longer detectable, is this a cure? And would it be possible to stop treatment altogether?