Topic : TKIs

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CML symptom swelling

Managing symptoms: swelling

A common side effects of medications such as Gleevec is swelling (edema). This usually occurs around the eyes or involve the eyelids, which can become puffy; or the legs, which can become swollen or feel heavy.
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Chronic Myelogenous Leukemia treatments

What do treatments do?

There are three types of approaches to treating the underlying defect in CML. The initial problem is too many white blood cells (WBCs) in the blood. A high WBC count on a blood test is often how CML is first detected.
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Chronic Myelogenous Leukemia Joint pain

Relieving joint pain

A common problem among people with CML is joint pain – achiness, stiffness, swelling or pain the bones. Sometimes the problem is just aging, but it can be a symptom of CML itself or the medication you’re taking.
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ASH 2013 – Can you stop treatment? The latest results

A few years ago, CML researchers started asking themselves two intriguing questions: If imatinib and other TKIs can suppress CML to such an extent that leukemia is no longer detectable, is this a cure? And would it be possible to stop treatment altogether?
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CML treatment goal

What are the treatment goals?

When you start taking a TKI to control your CML, there are important milestones along the way that indicate that you’re responding well to the medication.
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The see-saw story of Iclusig

Three TKIs are widely available to treat CML (Gleevec, Tasigna and Sprycel), and a fourth (Bosulif) has been approved in the U.S. and Europe.
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