There are three types of approaches to treating the underlying defect in CML.
The initial problem is too many white blood cells (WBCs) in the blood. A high WBC count on a blood test is often how CML is first detected.
A common problem among people with CML is joint pain – achiness, stiffness, swelling or pain the bones. Sometimes the problem is just aging, but it can be a symptom of CML itself or the medication you’re taking.
A few years ago, CML researchers started asking themselves two intriguing questions: If imatinib and other TKIs can suppress CML to such an extent that leukemia is no longer detectable, is this a cure? And would it be possible to stop treatment altogether?